Epibatidine, labeled with 125I. Epibatidine has analgesic activities, has been shown to function as an agonist at nicotinic acetylcholine receptors, and has been shown to bind muscarinic and serotonin......
詳細(xì)介紹
We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.
Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.
References for NEX358:
Garza, A., Huang, L.Z., Son, J.H., Winzer-Serhan, U.H. (2009), Expression of nicotinic acetylcholine receptors and subunit messenger RNAs in the enteric nervous system of the neonatal rat. Neuroscience, 158 (4): 1521-1529.
Huang, L.Z., Winzer-Serhan, U.H. (2006), Effects of paraformaldehyde fixation on nicotinic acetylcholine receptor binding in adult and developing rat brain sections. J Neurosci Methods, 153 (2): 312-317.
規(guī)格
濃度
87.9 µCi/mL
檢測方法
Radiometric
新鮮的很多天
First Monday of even Months
標(biāo)簽位置
Nominally Labeled
分子量
298.0
產(chǎn)品品牌名稱
NEN Radiolabeled Ligands
放射性同位素
I-125
放射性核素
125I
受體類型
Nicotinic
運輸條件
干冰
特殊訂購信息
This is a radioactive product - shipping address must have a license to receive radioactive materials.