Rabbit  Anti-IL6R抗體說(shuō)明書(shū)

FROM：Abcam

Catalog Number : ab128008   

Quantity size :   50ul  （dilute with pH 7.4  0.01 M PBS or antibody diluent ）

Background:

Interleukin 6 （IL6） is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer （IL6ST/GP130/IL6-beta）, a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported.                     

Specificity :        · anti- IL6R is a Rabbit polyclonal antibody unconjugated

 · specific for IL6R of Mouse, Rat, Human

·use for western blotting,elisa, immunoprecipitation   and immunohistochemistry

·  Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG

·  mol wt: 52kDa

Application:       · Western blotting 1:100-500

· Immunohistochemistry 1:100-500

· ELISA 1:500-1000

·  Optimal working dilutions must be determined by the end user.

Storage:     Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4 ºC.

Important Note: This product as supplied is intended for research use only, not for use in human,therapeutic or diagnostic applications.

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