欧美日本av在线免费观看,天天综合色天天综合色hd

FITC標(biāo)記的花生四烯酸15脂氧合酶2抗體是我司為您提供的高品質(zhì)抗體，公司生產(chǎn)的每一個(gè)抗體都經(jīng)過(guò)嚴(yán)格檢測(cè)和穩(wěn)定性測(cè)試，保證了結(jié)果的準(zhǔn)確性、敏感性、特異性。公司產(chǎn)品質(zhì)量有保證，*且我司擁有完善的市場(chǎng)營(yíng)銷體系、現(xiàn)代化管理體系和專業(yè)化物流配送系統(tǒng)，zui大程度滿足國(guó)內(nèi)外生命科研人員的產(chǎn)品需求，公司現(xiàn)經(jīng)營(yíng)抗體、ELISA試劑盒、標(biāo)準(zhǔn)品、染色液、染色試劑盒、培養(yǎng)基等多種科研產(chǎn)品，歡迎前來(lái)選購(gòu)！
英文名稱 Anti-15 Lipoxygenase 2/FITC
中文名稱 FITC標(biāo)記的花生四烯酸15脂氧合酶2抗體
別名 15 LO 2; 15 LOX 2; 15-lipoxygenase 2; 15-LOX-2; 15-LOX-B; ALOX15B; Arachidonate 15 lipoxygenase second type; Arachidonate 15 lipoxygenase type II; Arachidonate 15-lipoxygenase B; Arachidonate 15-lipoxygenase type II; LX15B_HUMAN.
說(shuō) 明書 100ug
研究領(lǐng)域腫瘤  心血管  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  新陳代謝
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, Pig,
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量 76kDa
性狀 Lyophilized or Liquid
濃度 2mg/1ml
免疫原 KLH conjugated synthetic peptide derived from human 15 Lipoxygenase 2
亞型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Lipoxygenases are a family of enzymes which dioxygenate unsaturated fatty acids, thus initiating lipoperoxidation of membranes, the synthesis of signalling molecules as well as inducing structural and metabolic changes in the cell. The Lox enzymes in mammals, 12-LO and 15-LO, are classified with respect to their positional specificity of the deoxygenation of their most common substrate, arachidonic acid. The metabolism of arachidonic acid leads to the generation of biologically active metabolites that have been implicated in cell growth and proliferation, as well as survival and apoptosis. 15-Lipoxygenase acts in physiological membrane remodeling and the pathogenesis of atherosclerosis, inflammation and carcinogenesis. It is highly regulated and expressed in a tissue- and cell-type-specific fashion. IL-4 and IL-13 play important roles in transactivating the 15-LO gene. Overexpression of 15-LO type 1 in prostate cancer contributes to the cancer progression by regulating IGF-1R expression and activation. 15-lipoxygenase, type II (15-LO2) is important for the conversion of arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. It is a cytoplasmic protein expressed primarily in cornea, lung, hair and prostate.

Function:
Converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while linoleic acid is less well metabolized.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in hair, prostate, lung and cornea.

Similarity:
Belongs to the lipoxygenase family.
Contains 1 lipoxygenase domain.
Contains 1 PLAT domain.

Database links: