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所在地區(qū):上海上海

聯系人:王經理 (經理)

技術文章

髓鞘堿性蛋白抗體,Anti-MBP抗體說明書

閱讀:613發(fā)布時間:2013-1-3

髓鞘堿性蛋白抗體,Anti-MBP抗體說明書         >>>>>>>點擊查看


Catalog Number : BYK- 0380R       
Quantity size :   0.1ml (dilute with pH 7.4    0.01 M PBS or antibody diluent )
 
Background: The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.
 
Specificity :   
        Anti- MBP is a mouse monoclonal antibody unconjugated                
        specific for MBP of  Human, Mouse, Rat, Goat, Rabbit, Sheep
        use for western blotting,elisa,immunoprecipitation and immunohistochemistry
        Protein G affinity chromatography purification, purity :>95%
        Isotype:  IgG
        mol wt:  33kDa
 
髓鞘堿性蛋白抗體,Anti-MBP抗體說明書Application :  
        Western blotting 1:100-500                
         Immunohistochemistry 1:100-500                 
         ELISA 1:500-1000                  
         Optimal working dilutions must be determined by the end user.
 
Storage: Store at -20 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4
 
髓鞘堿性蛋白抗體,Anti-MBP抗體說明書Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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