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Dihydroxyphenylethylamine, [3H(G)]- (Dopamine)

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珀金埃爾默醫(yī)學(xué)診斷產(chǎn)品（上海）有限公司

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Dihydroxyphenylethylamine (dopamine) radioligａnd tritiated at the 2,5,6,7,8 position. Dopamine functions as a neurotransmitter that binds dopamine receptors.

詳細(xì)介紹

Dihydroxyphenylethylamine is the natural agonist of dopamine receptors. These receptors are part of a group of G-protein coupled receptors (GPCRs) found in the central nervous system that play a role in motivation, pleasure, cognition, memory, learning, and fine motor control. Dopamine receptors are potential targets for attention deficit hyperactivity disorder (ADHD), schizophrenia, and hypertension.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (B_max), dissociation constants (K_d), association and dissociation rates (k_on and k_off), and inhibitor constants (K_i) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New Englａnd Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

規(guī)格

檢測(cè)方法	Radiometric
標(biāo)簽位置	Specifically Labeled
產(chǎn)品品牌名稱	NEN Radiochemicals
放射性同位素	H-3
放射性核素	³H
受體類型	Dopamine
運(yùn)輸條件	藍(lán)冰
特殊訂購(gòu)信息	This is a radioactive product - shipping address must have a license to receive radioactive materials.
治療領(lǐng)域	CNS & Neurologic
產(chǎn)品尺寸	1 mCi