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Membrane Target Systems: Muscarinic M3 (human) membrane preparation

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珀金埃爾默醫(yī)學(xué)診斷產(chǎn)品（上海）有限公司

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產(chǎn)品簡介

Cell membranes prepared from cells stably-transfected with human Muscarinic M3 receptor, in CHO-K1 cells.

詳細(xì)介紹

Membrane Target Systems are quality assured frozen membranes from cells that express recombinant or endogenous receptors.

We submit every batch of receptor to stringent quality control
testing that includes saturation radioligａnd binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPγS data is also provided for some of our Gi-coupled receptors.

Membranes are carefully prepared and ready for a variety of HTS applications, including radioligａnd binding (using either proximitymethods, such as FlashPlate, or classical filtration methods).

Products are packaged as frozen crude membrane preparations. One assay unit is defined as micrograms of protein, defined by competition binding assay (filtration). A complete product description and recommended protocol are included on the Product Information Sheet.

Some of our receptors may be restricted for sale in specified countries. Please inquire.

規(guī)格

檢測目標(biāo)類	GPCR
檢測目標(biāo)類型	Membrane preparation
檢測驗證	Binding
G-Alpha天然受體	Gq/G11
宿主細(xì)胞	CHO-K1
產(chǎn)品品牌名稱	Membrane Target Systems
受體類型	Acetylcholine (Muscarinic), Muscarinic
運輸條件	干冰
治療領(lǐng)域	Central Nervous System, Cardiovascular, Gastrointestinal
產(chǎn)品尺寸	400 units