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當(dāng)前位置:深圳艾利蒙生物科技有限公司>>技術(shù)文章>>奧貝膽酸雜質(zhì) 全套對(duì)照品
奧貝膽酸雜質(zhì) 全套對(duì)照品
深圳艾利蒙生物科技有限公司可提供奧貝膽酸雜質(zhì)全套,并隨貨提供COA證書,HPLC,NMR,MS圖譜,10mg/25mg/50mg/100mg等多種規(guī)格可選。
部分雜質(zhì)長(zhǎng)期備有現(xiàn)貨,可快速發(fā)貨,并可根據(jù)客戶需要提供雜質(zhì)定制服務(wù)。
奧貝膽酸的相關(guān)介紹:
適應(yīng)癥:
PBC又稱為原發(fā)性膽汁性膽管炎,是一種慢性進(jìn)展性自身免疫性肝病,會(huì)導(dǎo)致肝硬化或肝瘢痕。隨著肝硬化的發(fā)展,肝臟瘢痕組織的數(shù)量增加,肝功能衰竭,需要進(jìn)行肝臟移植。PBC用藥周期長(zhǎng),甚至需要終生用藥。
奧貝膽酸已被證明對(duì)治療非酒精性脂肪性肝炎(NASH)有效,美國(guó)FDA已授予其突破性療法認(rèn)定。
奧貝膽酸是肝臟和小腸表達(dá)的核受體激動(dòng)劑,臨床上主要是應(yīng)用于目前臨床藥物不應(yīng)答或者不耐受,并有很大風(fēng)險(xiǎn)的導(dǎo)致肝移植、肝硬化或者死亡的原發(fā)性膽汁性膽管炎的患者。
奧貝膽酸雜質(zhì) 全套對(duì)照品
奧貝膽酸雜質(zhì)為我司優(yōu)勢(shì)雜質(zhì),長(zhǎng)期備有庫(kù)存,發(fā)貨快。雜質(zhì)結(jié)構(gòu)式及更多其他雜質(zhì)對(duì)照品,可進(jìn)入我公司展臺(tái)詳細(xì)查看。
附:奧貝膽酸雜質(zhì)列表:
中文名稱 | 英文名稱 | CAS號(hào) |
奧貝膽酸標(biāo)準(zhǔn)品 | Obeticholic Acid | 459789-99-2 |
奧貝膽酸雜質(zhì)1 | (R)-4-((3R,5S,6R,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 865244-30-0 |
奧貝膽酸雜質(zhì)2 | (R)-4-((3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 915038-26-5 |
奧貝膽酸雜質(zhì)3 | (R)-4-((3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 915038-27-6 |
奧貝膽酸雜質(zhì)4 | (R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R)-6-ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
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奧貝膽酸雜質(zhì)5 | (R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 474-25-9 |
奧貝膽酸雜質(zhì)6 | (R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-((((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoyl)oxy)methyl)-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
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奧貝膽酸雜質(zhì)7 | (R)-4-((3R,5S,6S,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 1708092-13-0 |
奧貝膽酸雜質(zhì)8 | (3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-17-((R)-5-hydroxypentan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol | 1537866-49-1 |
奧貝膽酸雜質(zhì)9 | (R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 4651-67-6 |
奧貝膽酸雜質(zhì)10 | (R)-methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate | 10538-59-7 |
奧貝膽酸雜質(zhì)11 | (R)-methyl 4-((3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate |
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奧貝膽酸雜質(zhì)12 | (R)-4-((3R,5R,8S,9S,10R,13R,14S,17R)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 915038-24-3 |
奧貝膽酸雜質(zhì)13 | (R)-4-((3R,5S,6S,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
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奧貝膽酸雜質(zhì)14 | (4R)-4-((3R,5S,6R,7R,9S,10S,13R,14S,17R)-6-ethyl-3-(((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoyl)oxy)-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid | 1908444-28-9 |
奧貝膽酸雜質(zhì)15 | (R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
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奧貝膽酸雜質(zhì)16 | (R)-4-((5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7-dioxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid |
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奧貝膽酸雜質(zhì)17 | (R)-methyl 4-((3R,5R,8S,9S,10R,13R,14S,17R,Z)-6-ethylidene-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate | 863239-59-2 |
深圳艾利蒙生物科技有限公司主營(yíng)醫(yī)藥標(biāo)準(zhǔn)品及雜質(zhì)對(duì)照品,所有雜質(zhì)均提供HPLC,NMR,MS圖譜及CoA證: 舒更葡糖鈉雜質(zhì),骨化三醇雜質(zhì),阿法骨化醇雜質(zhì),艾地骨化醇雜質(zhì),西格列汀雜質(zhì),利伐沙班雜質(zhì),依托考昔雜質(zhì),左氧氟沙星雜質(zhì),阿加曲班雜質(zhì),利奈唑胺雜質(zhì),匹伐他汀雜質(zhì),利格列汀雜質(zhì),替格瑞洛雜質(zhì),阿哌沙班雜質(zhì),西他沙星雜質(zhì),伊馬替尼雜質(zhì),洛索洛芬鈉雜質(zhì),普瑞巴林雜質(zhì),環(huán)苯扎林雜質(zhì),鹽酸帕洛諾司瓊雜質(zhì)等。
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