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產(chǎn)品型號FITC
品 牌
廠商性質(zhì)經(jīng)銷商
所 在 地上海市
聯(lián)系方式:李小姐查看聯(lián)系方式
更新時間:2017-12-30 04:32:34瀏覽次數(shù):312次
聯(lián)系我時,請告知來自 環(huán)保在線Reactivity Human
Conjugate FITC
Laser Blue Laser
Emit N/A
Excite N/A
Reported Applications Flow Cytometric Analysis
Description: This product consists of two fluorochrome-conjugated monoclonal antibodies to distinguish human peripheral CD5+ T cells and CD19+ B cells. The UCHT2 monoclonal antibody (mouse IgG1, κ, HLDA # III518) reacts with human CD5, a 67 kDa protein expressed by the majority of thymocytes and mature T cells and a subset of B cells. Signaling through the CD5 molecule activates T cells and binding of CD5 to its ligand on B cells, CD72, and plays an important role in T-B interaction and proliferation. The HIB19 monoclonal antibody (mouse IgG1, κ, HLDA # V CD19.11) reacts with human CD19, a 95 kDa transmembrane glycoprotein. CD19 is expressed by B cells during all stages of development excluding the terminally differentiated plasma cells. Follicular dendritic cells also express CD19. Together CD21, CD81, Leu13, MHC class II, and CD19 form a multimolecular complex that associates with BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux and proliferation of B cells.
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