半乳糖凝集素3抗體/Anti-Galectin 3
別名：Galectin-3; 35 kDa lectin; Carbohydrate binding protein 35; CBP 35; CBP35; GAL 3; GAL3; Galactose specific lectin 3; Galactose-specific lectin 3; Galactoside binding protein; Galactoside-binding protein; GALBP; Galectin3 internal gene,included; Galectin-3; Galectin3; GALIG; GBP; IgE binding protein; IgE-binding protein; L 31; L 34; L-34 galactoside-binding lectin; L31; Laminin binding protein; Laminin-binding protein; Lectin galactose binding soluble 3; Lectin galactoside binding soluble 3; Lectin L 29; Lectin L-29; Lectin, galactose binding, soluble 3; LGALS 3; LGALS2; LGALS3; LGALS3 protein; MAC 2 antigen; Mac-2; MAC2; Macrophage galactose-specific lectin; MGC105387;Galectin- 3; LEG3_HUMAN.
Galectin-3是Galectin（半乳凝素）家族的一員，能識(shí)別糖蛋白和糖脂的特異性低聚糖結(jié)構(gòu)，參與多種生理和病理過(guò)程，包括細(xì)胞生長(zhǎng)和凋亡、細(xì)胞黏附、新生血管形成和腫瘤浸潤(rùn)與轉(zhuǎn)移等。Galectin-3在腫瘤的發(fā)生、發(fā)展及轉(zhuǎn)移中起重要作用。
Galectin-3在某些腫瘤組織中高表達(dá)，其在不同類型腫瘤，如結(jié)直腸癌、胃癌、胰腺癌、甲狀腺癌及肺癌等患者中的高表達(dá)水平，與低生存、腫瘤復(fù)發(fā)、預(yù)后差及對(duì)*藥物敏感性降低相關(guān)對(duì)于某些腫瘤，Galectin-3有可能成為一個(gè)有價(jià)值的診斷標(biāo)志和治療靶點(diǎn)。
半乳糖凝集素3抗體研究領(lǐng)域：腫瘤、免疫學(xué)、細(xì)胞凋亡、細(xì)胞粘附分子、細(xì)胞表面分子
Galectin 3抗體來(lái)源：兔
克隆類型：多克隆
交叉反應(yīng)：人、小鼠
產(chǎn)品用途：ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量：29kDa
細(xì)胞定位：細(xì)胞核、細(xì)胞漿、細(xì)胞膜、分泌型蛋白
性 狀：Lyophilized or Liquid
濃 度：1mg/ml
免 疫 原：KLH conjugated synthetic peptide derived from human Galectin 3:151-250/250
亞 型：IgG
純化方法：Affinity purified by Protein A
儲(chǔ) 存 液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
抗體供應(yīng)商：上海華壹生物科技有限公司
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