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MIG Human/重組人MIG （CXCL9）

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MIG Human/重組人MIG (CXCL9)產(chǎn)品編號(hào)：CHM-333
產(chǎn)品規(guī)格：5μg/20μg/1mg

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MIG Human/重組人MIG （CXCL9）

產(chǎn)品編號(hào)：CHM-333
產(chǎn)品規(guī)格：5μg/20μg/1mg
 

Synonyms Small inducible cytokine B9, CXCL9, Gamma interferon-induced monokine, MIG, chemokine （C-X-C motif） ligand 9, CMK, Humig, SCYB9, crg-10, monokine induced by gamma-interferon.
Introduction Chemokine （C-X-C motif） ligand 9 （CXCL9） is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by gamma interferon （MIG）. CXCL9 is a T-cell chemoattractant, which is induced by IFN-?. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.
Description MIG （monokine induced by gamma-interferon ） Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 103 amino acids and having a molecular mass of 11700 Dalton. The MIG is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder.
Formulation Lyophilized from a 0.2μm filtered concentrated （1.0mg/ml） solution in 20mM PB, pH 7.4, 50mM NaCl.
Solubility It is recommended to reconstitute the lyophilized MIG in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL9 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
Purity Greater than 97.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE.
Amino acid sequence TPVVRKGRCSCISTNQGTIHLQSLKDLKQFAPSPSCEKIEIIATLKNGVQTCLNPDS
ADVKELIKKWEKQVSQKKKQKNGKKHQKKKVLKVRKSQRSRQKKTT.
Biological Activity Determined by its ability to chemoattract human peripheral blood
T-Lymphocytes using a concentration range of 10.0-100.0 ng/ml.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.


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