細(xì)胞名稱

HEC-1-A人子宮內(nèi)膜腺癌細(xì)胞

描述

這株細(xì)胞及其亞株HEC-1-B是H. Kuramoto及其同事1968年從一位IA期子宮內(nèi)膜癌患者身上分離得到的。 PAF可以誘導(dǎo)其c-fos的表達(dá)。

動(dòng)物種別

人

性別

女

組織來(lái)源

腺癌;子宮;子宮內(nèi)膜炎

形態(tài)

上皮細(xì)胞樣

培養(yǎng)基和添加劑

McCOY's 5A(SIGMA,貨號(hào)M4892，添加NaHCO3 2.2g/L)，90%；優(yōu)質(zhì)胎牛血清，10%。 氣相：空氣，95%；二氧化碳，5%。 溫度：37攝氏度。

供應(yīng)限制

A。僅供研究之用。

REFERENCE

Kuramoto H . Studies of the growth and cytogenetic properties of human endometrial adenocarcinoma in culture and its development into an established line. Acta Obstet. Gynaecol. Jpn. 19: 47-58, 1972. PubMed: 4678779 Fogh J , et al. Absence of HeLa cell contamination in 169 cell lines derived from human tumors. J. Natl. Cancer Inst. 58: 209-214, 1977. PubMed: 833871 Fogh J , et al. One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice. J. Natl. Cancer Inst. 59: 221-226, 1977. PubMed: 327080 Presta M , et al. Modulation of plasminogen activator activity in human endometrial adenocarcinoma cells by basic fibroblast growth factor and transforming growth factor beta. Cancer Res. 48: 6384-6389, 1988. PubMed: 3263185 Maggi M , et al. Plaet-activating factor mediates an autocrine proliferative loop in the endometrial adenocarcinoma cell line HEC-1A. Cancer Res. 54: 4777-4784, 1994. PubMed: 7520361 Kuramoto H , et al. Establishment of a cell line of human endometrial adenocarcinoma in vitro. Am. J. Obstet. Gynecol. 114: 1012-1019, 1972. PubMed: 4673779 Hendricks DT , et al. FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines. Cancer Res. 57: 2112-2115, 1997. PubMed:9187105