Human VEGF165
產(chǎn)品編號:
100-20
別名:
Vascular Endothelial Growth Factor, VPF, Folliculoslate cell-derived growth factor, Glioma-derived endothelial cell mitogen
描述:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase （flt-1）, KDR gene product （the murine homolog of KDR is the flk-1 gene product） and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
氨基酸序列:
APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells （HUVEC） using a concentration range of 1.0-8.0 ng/ml.
交叉反應(yīng):
Cow, Green Algae, Guinea Pig, Hamster, Mouse, Pig, Rabbit, Rat, Sheep, Trout, Human, Chicken, Leech, Zebra Fish Embryo, Gelatin Microparticles, Rat + Chicken
研究領(lǐng)域:
血管生成/ 心血管癌癥
炎癥增殖

原產(chǎn)國:
USA
僅用于研究。不適用于診斷或治療。
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優(yōu)勢供應(yīng),*銷售,北京 Human VEGF165細(xì)胞因子Recombinant