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北京雅安達(dá)生物技術(shù)有限公司

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高品質(zhì)Recombinant Human IL-17 (IL-17A)5ug(PeproTech) 編號(hào):200-17

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Recombinant Human IL-17 (IL-17A)5ug(PeproTech) 編號(hào):200-17

 

Recombinant Human IL-17 (IL-17A)5ug(PeproTech) 編號(hào):200-17

 

貨號(hào):200-17
規(guī)格:5ug
產(chǎn)地:PeproTech
Biological Activity: Assay #1: The ED50 as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximay 2 ng/ml. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family. 
Cross Reactivity: Assay #2: Measured by its ability to induce IL-6 production by NHDF cells.  IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.0 kDa disulfide-linked homodimer of two 136 amino acid polypeptide chains. Mouse 
Description: Synonyms: IL-17,CTLA-8. The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Country of Origin: USA

 

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