名稱：現(xiàn)貨原裝|Recombinant Human IL-4

貨號：200-04
規(guī)格：20ug 
產地：PeproTech
Biological Activity: The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is ≤ 0.2 ng/ml, Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. corresponding to a specific activity of ≥ 5 x 106 units/mg.
Purity: Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues. Greater than 98% by SDS-PAGE gel and HPLC analyses. 
Description: Synonyms: BCGF,BCDF,B cell stimulating factor （BSF-1）. 
T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, which favor a humoral immune response. Country of Origin: USA 
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