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鼠爪壓力測(cè)痛儀

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上海玉研科學(xué)儀器有限公司是一家專業(yè)為動(dòng)物實(shí)驗(yàn)、動(dòng)物研究領(lǐng)域提供科學(xué)儀器和技術(shù)服務(wù)的公司。我們著力引進(jìn)國(guó)外的*科學(xué)儀器和實(shí)踐經(jīng)驗(yàn)，選擇使用廣泛、應(yīng)用成熟、性能*的實(shí)驗(yàn)儀器和實(shí)驗(yàn)方法，為國(guó)內(nèi)實(shí)驗(yàn)室建設(shè)、研究課題進(jìn)展提供科學(xué)、合理的解決方案?！　∮裱袃x器專注于生理、藥理、毒力等動(dòng)物實(shí)驗(yàn)和研究的相關(guān)領(lǐng)域，為客戶提供動(dòng)物檢驗(yàn)、生理機(jī)能、呼吸血壓麻醉、行為學(xué)、肺功能研究等多方面的科學(xué)儀器產(chǎn)品和相關(guān)服務(wù)。我們已經(jīng)與國(guó)際上眾多科學(xué)儀器研發(fā)機(jī)構(gòu)建立了良好的合作渠道，并取得了多家廠商在中國(guó)的代理權(quán)，如：Vitalab、Pinnacle、Harvard、Starr Life、IITC、Stoelting、Union Biometrica、Stoelting等等?！　∮裱袃x器致力于真誠(chéng)為客戶帶來(lái)價(jià)值。　　我們的宗旨：客戶的肯定是我們的成功?！　∥覀兊姆?wù)理念：開拓、創(chuàng)新、務(wù)實(shí)、服務(wù)，為客戶提供專業(yè)、優(yōu)質(zhì)的服務(wù)。　　我們的企業(yè)使命：為動(dòng)物實(shí)驗(yàn)基礎(chǔ)研究領(lǐng)域提供技術(shù)產(chǎn)品和專業(yè)服務(wù)，為祖國(guó)的科技進(jìn)步和健康事業(yè)發(fā)展做出更大貢獻(xiàn)?！∮裱袃x器公司——專注于動(dòng)物實(shí)驗(yàn)設(shè)備的技術(shù)產(chǎn)品和專業(yè)服務(wù)　　動(dòng)物手術(shù)方案：, , , 監(jiān)護(hù)儀, 動(dòng)物保溫, 電凝, 手術(shù)器械, 縫合器, 快速消毒器等　　生理指標(biāo)檢測(cè)：血壓, 組織血流量檢測(cè), 心電監(jiān)護(hù), 脈搏血氧, 呼吸監(jiān)測(cè), 心電遙測(cè)等　　檢驗(yàn)類儀器：血液分析, 生化檢驗(yàn), 凝血分析, 尿液, 血?dú)? 血小板聚集等　　神經(jīng)藥理：行為學(xué), 炎癥疼痛, 腦立體定位, 微透析, 腦脊髓損傷, 腦切片磨具, Von Frey觸覺(jué)測(cè)量等　　毒理設(shè)備：口鼻部給藥, 全身暴露給藥, 吸煙機(jī), 氣溶膠發(fā)生, 肺功能研究, 呼吸代謝測(cè)量, 氣溶膠肺部定量給藥等　　動(dòng)物影像設(shè)備：micro-CT, X光機(jī), B超, 視網(wǎng)膜成像等　　其他設(shè)備：動(dòng)物標(biāo)記, 傷口縫合器, 箱, 鼠, , 等

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鼠爪壓力測(cè)痛

鼠爪壓力測(cè)痛儀產(chǎn)品信息

鼠爪壓力測(cè)痛儀（小鼠壓痛儀，壓力疼痛測(cè)試儀，Randall Selitto Paw Pressure Test Apparatus Mice and Rats）（測(cè)量并記錄動(dòng)物產(chǎn)生逃避反應(yīng)時(shí)的瞬間壓力，以測(cè)定動(dòng)物機(jī)械鈍痛的痛覺(jué)閾限，操作簡(jiǎn)便，更多詳情敬請(qǐng)）

型號(hào)2500型

Randall&Selitto測(cè)試，通過(guò)逐步提高作用于動(dòng)物爪子上的機(jī)械壓力，逼近動(dòng)物的疼痛閾限，測(cè)量并記錄動(dòng)物產(chǎn)生逃避反應(yīng)時(shí)的瞬間壓力，以測(cè)定動(dòng)物機(jī)械鈍痛的痛覺(jué)閾限。

與熱痛不同，鼠爪壓力疼痛測(cè)痛儀用于機(jī)械壓痛和鈍痛的痛覺(jué)測(cè)量，常用于辨別左右爪不同的痛覺(jué)反應(yīng)，多涉及脊髓神經(jīng)過(guò)程，人工辨別動(dòng)物縮腿反應(yīng)，并用踏板控制馬達(dá)的起止。

Once again it has benn designed a first in the pain testing research field, the very first digitally controlled paw pressure meter. The unit allows the user to attain data for analgesic drug testing via the Randall Selitto method.

This hand held instrument applies a force to the extremity of the test subjects. “Live” readings are provided of whatever force is applied at any moment with “Peak and Hold” showing the last maximum force applied during the test. Additional “Pressure Applicators” available.

鼠爪壓力疼痛測(cè)試儀主要特點(diǎn)

? 適用于大鼠和小鼠

? 精確度為0.1克，壓力400克

? 數(shù)字顯示功能

? 配置腳踏控制器

? RS-232輸出

鼠爪壓力疼痛測(cè)試儀型號(hào)參數(shù)

Part #	Description
2660	Rat and mouse slings individual
2660RXS	Rat sling suit, x-small 100-150 grams
2660RS	Rat sling suit, small 150-250 grams
2660RM	Rat sling suit, medium 250-350 grams
2660RL	Rat sling suit, large 350-500 grams
2660RXL	Rat sling suit, x-large + 500 grams
2660MS	Mouse sling suit, small up to 25 grams
2660MM	Mouse sling suit, medium 25-30 grams

部分參考文獻(xiàn)

Recombinant human lactoferrin prevents NSAID‐induced intestinal bleeding in rodents

EJ Dial, AJ Dohrman, JJ Romero… - Journal of pharmacy …, 2005 - Wiley Online Library

... two hours the rats were placed in a Randall-Sellito appa- ratus (IITC Inc., Woodlａnd Hills, CA ...
indometacin (10mgkgà1) or RHLF plus indometacin and tested for sensitivity to pressure/pain
on ... P<0.05 vs saline control inflamed paw; #P<0.05 vs saline control non-inflamed paw. ...

[HTML] High-fat diet-induced neuropathy of prediabetes and obesity: effect of PMI-5011, an ethanolic extract of Artemisia dracunculus L.

P Watcho, R Stavniichuk, DM Ribnicky… - Mediators of …, 2010 -

Hindawi Publishing Corporation. ... 2 Temperature Controller with RET-3 Temperature probe and
HL-1, Heat Lamp (Physitemp Instruments, Inc., Clifton, NJ ... A thermal stimulation meter (IITC model
336 TG Combination Tail Flick and Paw algesia meter, IITC Life Science, Woodland ...

Investigation of the anti-inflammatory, antinociceptive effect of ellagic acid as measured by digital paw pressure via the Randall-Selitto meter in male Sprague-Dawley …

J Gainok, R Daniels, D Golembiowski… - AANA …, 2011 -

... The Randall-Selitto IITC 2500 Digital Paw Pressure Meter (IITC Life Science Inc, Woodlａnd Hills ...
A single rat paw was stimu- lated with the Randall-Selitto IITC 2500, and a reading ... Ketorolac
(Syntax Corporation, Palo Alto, California) is a nonselective COX inhibitor tbat has been ...

[HTML] Analgesic effects of an ethanol extract of the fruits of Xylopia aethiopica (Dunal) A. Rich (Annonaceae) and the major constituent, xylopic acid in murine …

E Woode, EO Ameyaw, E Boakye-Gyasi… - Journal of pharmacy & …, 2012 - europepmc.org

... stimulus was measured with the radiant heat source method using the IITC Analgesia Meter
(Model 336, IITC Life Science Inc., Woodlａnd Hills ... paw pressure test, an inflammatory pain model,
widely used for quantification of thresholds of the rat hind paw withdrawal reflex to ...

[PDF] Characterization of a rat model of metastatic prostate cancer bone pain

PD De Ciantis, K Yashpal, J Henry, G Singh - J Pain Res, 2010 -

... An IITC Model 2500 Randall–Selitto Paw Pressure Meter (IITC Life Science Inc ... were fixed to a
microtome (Reichert-Jung 2040 Microtome; Reichert Inc., Depew, NY ... for each sample were recon-
structed with Cobra_EXXIM software (Exxim Computing Corporation, Pleasanton, CA ...

Randall-Selitto test: a new approach for the detection of neuropathic pain after spinal cord injury

E Santos-Nogueira, E Redondo Castro… - Journal of …, 2012 -

... by using the Randall-Selitto electronic algesimeter (IITC 2500 Digital Paw Pressure Meter, IITC
Life Science ... We therefore pooled right and left paw measurements to simplify statistical analyses. ...
The statistical software packages Statistica, v. 9 (StatSoft Inc., Tulsa, OH) and SPSS v ...

Anti-hyperalgesic and anti-allodynic activities of capillarisin via suppression of inflammatory signaling in animal model

S Khan, O Shehzad, J Chun, RJ Choi, S Park… - Journal of …, 2014 - Elsevier

... was evaluated at different time points (2, 4, and 6 h) using the Randall Selitto (Digital Paw
Pressure Randall Selitto Meter, IITC Life Science Inc). ... Briefly, paw skin tissues were removed
at the end of treatment, and total protein was extracted by using RIPA lysis buffer (Pierce ...

[HTML] The α7 nicotinic ACh receptor agonist compound B and positive allosteric modulator PNU‐120596 both alleviate inflammatory hyperalgesia and cytokine …

G Munro, RR Hansen, HK Erichsen… - British journal of …, 2012 - Wiley Online Library

... Immediately afterwards, the rat was gently restrained by the investigator before the application
of progressively increasing mechanical pressure to the mid-hind paw region using an electronic
version of the Randall-Selitto device (IITC Life Science Inc., Woodlａnd Hills ...

Peripheral Antinociception of a Chalcone, Flavokawin B and Possible Involvement of the Nitric Oxide/Cyclic Guanosine Monophosphate/Potassium Channels …

MN Kamaldin, MN Akhtar, AS Mohamad, N Lajis… - Molecules, 2013 -

... Ltd., China) to ensure complete dissolution of the chemicals. ... the right hind paw of the rat. The
mechanical nociceptive threshold was measured using a digital Randall Selitto paw pressure
test apparatus (Model 2500, IITC Life Science, Woodlａnd Hills, CA, USA). ...

Phagocytic microglial phenotype induced by glibenclamide improves functional recovery but worsens hyperalgesia after spinal cord injury in adult rats

E Redondo‐Castro, J Hernández… - European Journal of …, 2013 - Wiley Online Library

... 2013 Federation of European Neuroscience Societies and John Wiley & Sons Ltd. ... acclimated
to the belt compartment of a Digigait Imaging system (Mouse Specifics Inc., Boston, MA ... was
performed by means of a digital paw pressure meter device (IITC 2500, IITC Life Science ...