120841
胰高血糖素樣肽2/GLP-2 Peptide
序列號(hào):146-178
純化方法:HPLC
產(chǎn)品應(yīng)用:Biological activity
Immunology research
Quantity size:
0.5mg
Source:
Synthetic Peptide
Form:
lyophilized powde
Purity:
≥95% (Purified by HPLC)
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Biological activity
Immunology research
Background:
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq].
GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability.
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上海華壹生物科技有限公司
Shanghai HuaYi Bio-technology Co.,Ltd
更多多肽介紹:胰高血糖素樣肽2/GLP-2 Peptide
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